Construction of anatomically correct models of mouse brain networks

نویسندگان

  • Bruce H. McCormick
  • Wonryull Koh
  • Yoonsuck Choe
  • Louise C. Abbott
  • John Keyser
  • David Mayerich
  • Zeki Melek
  • Purna Doddapaneni
چکیده

The Mouse Brain Web, a federated database, provides for the construction of anatomically correct models of mouse brain networks. Each web page in this database provides the position, orientation, morphology, and putative synapses for each biologically observed neuron. The Mouse Brain Web has been designed to support (1) mapping of the spatial distribution and morphology of neurons by type; (2) wiring of the network – synaptic assembly; (3) projection of neuron morphology and synapses to geometric multi-compartmental models; (4) search for motifs and canonical circuits in the brain networks using customized web-crawlers; and (5) the mapping of anatomically correct networks to physiologically correct network simulations.

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عنوان ژورنال:
  • Neurocomputing

دوره 58-60  شماره 

صفحات  -

تاریخ انتشار 2004